Back pain
Within the context of psychoactive substances, this effect can occur through tactile enhancement which increases the symptoms of a pre-existing condition which is usually otherwise not noticeable, as a result of muscle tension, as a result of kidney problems, and also as a symptom of withdrawal symptoms from substances which are used for pain relief such as opioids.
Back pain is most commonly induced under the influence of heavy dosages of stimulating psychedelics compounds, such as LSD, 2C-B, and mescaline.