Confusion can be described as a state of being bewildered or unclear in one’s mind about something. Within the context of substance use, it is commonly experienced as a persistent inability to grasp or comprehend concepts and situations which would otherwise be perfectly understandable during sobriety. The intensity of this effect seems to to be further increased when a person is unfamiliar with the substance they are on.

Confusion is often accompanied by other coinciding effects such as delirium, delusions, and short term memory suppression in a manner which further increases the person's lack of comprehension. It is most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, cannabinoids and deliriants. However, it can also occur to a lesser extent under the influence of heavy dosages of benzodiazepines and antipsychotics.

psychoactive substances

Compounds which may cause this effect commonly include:

3-MMC, 3C-E, 4-AcO-DMT, 4-FA, 5-MeO-DMT, Alprazolam, DPT, Datura, Dextropropoxyphene, DiPT, Diphenhydramine, ETH-LAD, Efavirenz, Harmala alkaloids, LSM-775, MDMA, MDPV, MET, PARGY-LAD, PRO-LAD, Psilocin, Psilocybin mushrooms, Salvinorin A, Temazepam, Zolpidem

See also

  • Delirium
  • Analysis suppression
  • Memory suppression


Documentation written by Josie Kins