Irritability enhancement

Irritability enhancement can be described as a cognitive effect which results in heightened feelings of stress, irritability, annoyance, and anger. These feelings are often further intensified by other accompanying effects such as anxiety, paranoia, and ego inflation.

This effect can sometimes result in a certain subset of people presenting a greater tendency towards exhibiting violent behaviors. However, the chances of somebody responding in such a way depends on the individual and differs wildly between people. It is also worth noting that an increased propensity towards violence typically only affects those who were already susceptible to aggressive behaviors.

Irritability is often accompanied by other coinciding effects such as anxiety, paranoia, and ego inflation. It is most commonly induced during the after effects of heavy dosages of stimulant compounds, such as cocaine, methamphetamine, and methylphenidate. However, it can also occur during the withdrawal symptoms of almost any substance and to a lesser extent under the influence of alcohol intoxication.[1]


psychoactive substances

Compounds which may cause this effect commonly include:

2-Aminoindane, 2-FA, 2-FMA, 3,4-CTMP, 3-FA, 3-FEA, 3-FMA, 3-FPM, 3-MMC, 4-FA, 4-FMA, 4F-EPH, 4F-MPH, 5-APB, 5-MAPB, 6-APB, 6-APDB, A-PHP, A-PVP, Alcohol, Alprazolam, Amphetamine, Butylone, Caffeine, Clonazepam, Clonazolam, Cocaine, Creatine, Desoxypipradol, Diazepam, Dichloropane, Diclazepam, Diphenhydramine, ETH-CAT, Ethylone, Ethylphenidate, Etizolam, Flubromazepam, Flubromazolam, Hexedrone, Hexen, Isopropylphenidate, Lisdexamfetamine, MDA, MDAI, MDEA, MDMA, MDPV, Mephedrone, Methamphetamine, Methiopropamine, Methylnaphthidate, Methylone, Methylphenidate, Mexedrone, Mirtazapine, NEP, NM-2-AI, Nifoxipam, Noopept, Pentedrone, Piracetam, Prolintane, Propylhexedrine, Stimulant, Tyrosine, U-47700, Zopiclone


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Documentation written by Josie Kins