Sleepiness can be described as an increased urge to sleep and growing inability to stay awake without feeling a decrease in one's physical energy levels. Unlike sedation, this effect does not necessarily decrease physical energy levels but instead decreases wakefulness, resulting in a propensity for tired, clouded, and sleep-prone behavior. This can lead into a decreased motivation to perform tasks, as the increase in one's desire to sleep begins to outweigh other considerations. Prolonged exposure without appropriate rest can lead to cognitive fatigue and a range of other cognitive suppressions.

Drugs with this specific mode of action include melatonin, cannabinoids and DPH. They are collectively referred to as hypnotics, the opposite of eugeroics.

psychoactive substances

Compounds which may cause this effect commonly include:

5-Hydroxytryptophan, Alcohol, Alprazolam, Cannabis, Clonazepam, Clonazolam, Codeine, Datura, Dextromethorphan & Diphenhydramine, Diazepam, Diclazepam, Diphenhydramine, Etizolam, Flubromazepam, Flubromazolam, Haloperidol, Hydrocodone, Kratom, Melatonin, Nifoxipam, Phenibut, Quetiapine, Risperidone

See also


Documentation written by Josie Kins