Suicidal ideation

Suicidal ideation can be described as the experience of compulsive suicidal thoughts and a general desire to end one's own life. These thoughts patterns and desires range in intensity from fleeting thoughts to an intense fixation which is often accompanied by severe depression. This effect can create a predisposition to other self-destructive behaviors such as self-harm or drug abuse and, if left unresolved, can eventually lead to attempts of suicide.

Suicidal ideation can be a manifestation of a number of things including adverse reactions to certain substances, mental illness, traumatic life events, and interpersonal problems. However, in the context of psychoactive substance usage, it is most commonly with associated various antidepressants of the selective serotonin reuptake inhibitor class.


psychoactive substances

Compounds which may cause this effect commonly include:

amitriptyline, amoxapine, bupropion, citalopram, clomipramine, cyclobenzaprine, desipramine, dosulepin, doxepin, duloxetine, escitalopram, fluoxetine, fluvoxamine, imipramine, lithium carbonate, lofepramine, maprotiline, mianserin, mirtazapine, nefazodone, norepinephrine, nortriptyline, paroxetine, phenelzine, protriptyline, reboxetine, sertraline, sulpiride, tranylcypromine, trazodone, trimipramine, venlafaxine, amisulpride, aripiprazole, atomoxetine, bromperidol, chlorpromazine, clozapine, fluphenazine, haloperidol, leponex, olanzapine, paliperidone, perphenazine, pipamperone, prochlorperazine, quetiapine, risperidone, sulpiride, thioridazine, thiothixene, trifluoperazine, ziprasidone[1]


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Documentation written by Josie Kins