Tactile suppression can be described as a decrease in one's ability to feel their sense of touch in a manner which can result a general numbness across the body. At higher levels, this can eventually increase to the point where physical sensations have been completely blocked and the body is fully anesthetized.
Tactile suppression is often accompanied by other coinciding effects such as pain relief and physical euphoria. It is most commonly induced under the influence of moderate dosages of dissociative compounds such as ketamine, PCP, and DXM. However, it can also occur under the influence of opioids and certain GABAergic depressants.
Compounds which may cause this effect commonly include:
2-Fluorodeschloroketamine, 3-HO-PCE, 3-HO-PCP, 3-MeO-PCE, 3-MeO-PCMo, 3-MeO-PCP, 4-MeO-PCP, Acetylfentanyl, Alcohol, Benzydamine, Buprenorphine, Codeine, Datura, Deschloroketamine, Desomorphine, Dextromethorphan, Dextropropoxyphene, Diacetylmorphine, Dihydrocodeine, Diphenhydramine, Diphenidine, Ephenidine, Ethylmorphine, Fentanyl, Hydrocodone, Hydromorphone, Ketamine, Kratom, Methadone, Methoxetamine, Methoxphenidine, Morphine, Nitrous, O-Desmethyltramadol, O-PCE, Oxycodone, Oxymorphone, PCE, PCP, Pethidine, Sufentanil, Tapentadol, Tramadol, U-47700
Documentation written by Josie Kins / Cocoa