Wakefulness can be described as an increased ability to stay conscious without feeling tired combined with a decreased need to sleep. It is contrasted with stimulation in that it does not directly increase one's energy levels above a normal baseline but instead produces feelings of a wakeful, well-rested and alert state.

Wakefulness is most commonly induced under the influence of moderate dosages of a wide variety of compounds such as stimulants, nootropics, and psychedelics. However, it is worth noting that the few compounds which selectively induce this effect without a number of other accompanying effects are referred to as eugeroics or wakefulness-promoting agents. These include modafinil, armodafinil, and noopept.

psychoactive substances

Compounds which may cause this effect commonly include:

1P-ETH-LAD, 1P-LSD, 2-Aminoindane, 2-FA, 2-FMA, 25B-NBOH, 25B-NBOMe, 25C-NBOH, 25C-NBOMe, 25D-NBOMe, 25I-NBOH, 25I-NBOMe, 25N-NBOMe, 2C-B, 2C-B-FLY, 2C-C, 2C-E, 2C-I, 2C-P, 2C-T-2, 2C-T-7, 3,4-CTMP, 3-FA, 3-FEA, 3-FMA, 3-FPM, 3-MMC, 3C-E, 4-AcO-DET, 4-AcO-MET, 4-AcO-MiPT, 4-FA, 4-FMA, 4-HO-DET, 4-HO-MET, 4-HO-MiPT, 4F-EPH, 4F-MPH, 5-APB, 5-MAPB, 5-MeO-DALT, 5-MeO-DMT, 5-MeO-DiBF, 5-MeO-MiPT, 6-APB, 6-APDB, A-PHP, A-PVP, AL-LAD, ALD-52, Adrafinil, Alpha-GPC, Amphetamine, Aniracetam, Armodafinil, Ayahuasca, Bromantane, Bromo-DragonFLY, Bufotenin, Butylone, Caffeine, Citicoline, Cocaine, Coluracetam, Creatine, DOB, DOC, DOI, DOM, DPT, Datura, Desoxypipradol, Dextromethorphan, Dichloropane, Diphenhydramine, ETH-CAT, ETH-LAD, Escaline, Ethylone, Ethylphenidate, Hexedrone, Hexen, Ibogaine, Isopropylphenidate, LSA, LSD, LSM-775, LSZ, Lisdexamfetamine, MDA, MDAI, MDEA, MDMA, MDPV, MET, Mephedrone, Mescaline, Methamphetamine, Methiopropamine, Methylnaphthidate, Methylone, Methylphenidate, Mexedrone, MiPT, Modafinil, N-Methylbisfluoromodafinil, NEP, NM-2-AI, Nicotine, Noopept, Oxiracetam, PARGY-LAD, PMMA, PRO-LAD, Pentedrone, Phenylpiracetam, Piracetam, Pramiracetam, Prolintane, Propylhexedrine, TMA-2, TMA-6, Theacrine, Tramadol, Tyrosine, ΑMT

See also

  • Stimulation
  • Sleepiness


Documentation written by Josie Kins