Wakefulness can be described as an increased ability to stay conscious without feeling tired combined with a decreased need to sleep. It is contrasted with stimulation in that it does not directly increase one's energy levels above a normal baseline but instead produces feelings of a wakeful, well-rested and alert state.

Psychoactive compounds which primarily induce this specific effect are referred to as eugeroics or wakefulness-promoting agents. These include modafinil, armodafinil, and noopept. However, it is worth noting that many classes of compound such as stimulants, nootropics, and psychedelics can also indirectly induce this state alongside of a wide variety of other effects.

psychoactive substances

Compounds which may cause this effect commonly include:

1P-ETH-LAD, 1P-LSD, 2-Aminoindane, 2-FA, 2-FMA, 25B-NBOH, 25B-NBOMe, 25C-NBOH, 25C-NBOMe, 25D-NBOMe, 25I-NBOH, 25I-NBOMe, 25N-NBOMe, 2C-B, 2C-B-FLY, 2C-C, 2C-E, 2C-I, 2C-P, 2C-T-2, 2C-T-7, 3,4-CTMP, 3-FA, 3-FEA, 3-FMA, 3-FPM, 3-MMC, 3C-E, 4-AcO-DET, 4-AcO-MET, 4-AcO-MiPT, 4-FA, 4-FMA, 4-HO-DET, 4-HO-MET, 4-HO-MiPT, 4F-EPH, 4F-MPH, 5-APB, 5-MAPB, 5-MeO-DALT, 5-MeO-DMT, 5-MeO-DiBF, 5-MeO-MiPT, 6-APB, 6-APDB, A-PHP, A-PVP, AL-LAD, ALD-52, Adrafinil, Alpha-GPC, Amphetamine, Aniracetam, Armodafinil, Ayahuasca, Bromantane, Bromo-DragonFLY, Bufotenin, Butylone, Caffeine, Citicoline, Cocaine, Coluracetam, Creatine, DOB, DOC, DOI, DOM, DPT, Datura, Desoxypipradol, Dextromethorphan, Dichloropane, Diphenhydramine, ETH-CAT, ETH-LAD, Escaline, Ethylone, Ethylphenidate, Hexedrone, Hexen, Ibogaine, Isopropylphenidate, LSA, LSD, LSM-775, LSZ, Lisdexamfetamine, MDA, MDAI, MDEA, MDMA, MDPV, MET, Mephedrone, Mescaline, Methamphetamine, Methiopropamine, Methylnaphthidate, Methylone, Methylphenidate, Mexedrone, MiPT, Modafinil, N-Methylbisfluoromodafinil, NEP, NM-2-AI, Nicotine, Noopept, Oxiracetam, PARGY-LAD, PMMA, PRO-LAD, Pentedrone, Phenylpiracetam, Piracetam, Pramiracetam, Prolintane, Propylhexedrine, TMA-2, TMA-6, Theacrine, Tramadol, Tyrosine, ΑMT

See also

  • Stimulation
  • Sleepiness


Documentation written by Josie Kins