Appetite enhancement

Appetite enhancement (also known as "the munchies" [1] ) can be described as the experience of a distinct increase in a person's sense of hunger and appetite. This results in both an increased desire to eat food and an increased enjoyment of its taste.

Appetite enhancement is most commonly induced under the influence of moderate dosages of orexigenic compounds, such as cannabinoids, [2] mirtazapine, [3] and quetiapine [4] . However, it may also occur under the influence of other compounds such as GABAergic depressants, tricyclic antidepressants (TCAs), tetracyclic antidepressants, first-generation antihistamines, most antipsychotics, and many steroid hormones.


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  2. Berry, Elliot M., and Raphael Mechoulam. "Tetrahydrocannabinol and endocannabinoids in feeding and appetite." Pharmacology & therapeutics 95.2 (2002): 185-190. |
  3. Montgomery, S. A. (1995). Safety of mirtazapine: a review. International clinical psychopharmacology, 10, 37-45. |
  4. Common side effects of seroquel (rxlist) |




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