Empathy, affection, and sociability enhancement

Empathy, affection, and sociability enhancement is the experience of a mind state that is dominated by intense feelings of compassion, talkativeness, and happiness. [1] [2] [3] The experience of this effect creates a wide range of subjective changes to a person's perception of their feelings towards other people and themselves. These are described and documented in the list below:

  • Increased sociability and the feeling that communication comes easier and more naturally.
  • Increased urge to communicate or express one's affectionate feelings towards others, even if they happen to be strangers.
  • Increased feelings of empathy, love, and connection with others.
  • Increased motivation to resolve social conflicts and improve interpersonal relationships.
  • Decreased negative emotions and mental states such as stress, anxiety, and fear.
  • Decreased insecurity, defensiveness, and fear of emotional injury or rejection from others.
  • Decreased irritability, aggression, anger, and jealousy.

Empathy, affection, and sociability enhancement is often accompanied by other coinciding effects, such as stimulation, personal bias suppression, motivation enhancement, and anxiety suppression. It is most commonly induced under the influence of moderate dosages of entactogenic compounds, such as MDMA [4] [5] , 4-FA [6] [7] , and 2C-B [8] [9] . However, it can also subtly occur to a much lesser extent under the influence of GABAergic depressants and certain stimulants. [10]


  1. Nichols, D. E. (1986). Differences between the mechanism of action of MDMA, MBDB, and the classic hallucinogens. Identification of a new therapeutic class: entactogens. Journal of psychoactive drugs, 18(4), 305-313. | https://doi.org/10.1080/02791072.1986.10472362
  2. The Great Entactogen - Empathogen Debate (from the Newsletter of the Multidisciplinary Association for Psychedelic Studies, MAPS - Volume 4 Number 2 Summer 1993 - pp 47-49 | https://www.maps.org/news-letters/v04n2/04247eed.html
  3. Bedi, G., Hyman, D., & de Wit, H. (2010). Is ecstasy an “empathogen”? Effects of±3, 4-methylenedioxymethamphetamine on prosocial feelings and identification of emotional states in others. Biological psychiatry, 68(12), 1134-1140. | https://dx.doi.org/10.1016%2Fj.biopsych.2010.08.003
  4. Scahill, L., & Anderson, G. M. (2010). Is ecstasy an empathogen?. Biological psychiatry, 68(12), 1082. | https://dx.doi.org/10.1016%2Fj.biopsych.2010.10.020
  5. 4-Fluoroamphetamine(4-FA) – Critical Review Report | http://www.who.int/medicines/access/controlled-substances/5.4_4-FA_CRev.pdf?ua=1
  6. González, D., Torrens, M., & Farré, M. (2015). Acute effects of the novel psychoactive drug 2C-B on emotions. BioMed research international, 2015. | https://dx.doi.org/10.1155%2F2015%2F643878
  7. Wardle, M. C., Garner, M. J., Munafò, M. R., & de Wit, H. (2012). Amphetamine as a social drug: effects of d-amphetamine on social processing and behavior. Psychopharmacology, 223(2), 199-210. | https://dx.doi.org/10.1007%2Fs00213-012-2708-y




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